Thursday, August 1, 2013

Where/how do gingers get their hideous pigmentation from?

red hair melanocortin 1 receptor
 on http://reference.findtarget.com/search/Haplogroup_R1b_%28Y-DNA%29
red hair melanocortin 1 receptor image






Serious question lah. Is it like somebody growing with a 6th finger and such? Like just a small handicap or is it just more like blue eyes with blond hair?


Answer
The pigment pheomelanin gives red hair its distinctive colour. Red hair has far more of the pigment pheomelanin than it has of the dark pigment eumelanin.

The genetics of red hair, discovered in 1997, appear to be associated with the melanocortin-1 receptor (MC1R), which is found on chromosome 16. Red hair is associated with fair skin colour due to low concentrations of eumelanin throughout the body of those with red hair. This lower melanin-concentration confers the advantage that a sufficient concentration of important Vitamin D can be produced under low light conditions. However, when UV-radiation is strong (like in regions close to the equator) the lower concentration of melanin leads to several medical disadvantages, such as a higher risk of skin cancer.

The MC1R recessive variant gene that gives people red hair and fair skin is also associated with freckles, though it is not uncommon to see a redhead without freckles.

Even a couple that does not have red hair can have a baby with red hair because they could be carriers of the gene, so watch what you say, your baby could come out a ginger!

What nationality do freckles originate from?




ali


I'm not talking freckles that come from tanning, i'm talking generic freckles.


Answer
Nationalities most likely to have freckles:
Irish
Scottish
Welsh
Swedish
Norwegian

Freckles are small tan spots of melanin on the exposed skin or membrane of people with fair complexions, though rarely people of African descent get them.

Having freckles is genetic and is related to the presence of the melanocortin-1 receptor MC1R gene variant, which is dominant. Freckling can also be triggered by long exposure to sunlight, such as suntanning. When the sun's rays penetrate the skin, they activate melanocytes which can cause freckles to become darker and more numerous, although the distribution of melanin is not the same. Fair hair such as blonde, or more commonly red hair, are usually common with the genetic factor of freckles, but none so much as fair or pale skin.

Freckles are predominantly found on the face, although they may appear on any skin exposed to the sun. Freckles are rare on infants, and more common on children before puberty; they are less common on adults.

Children who do not produce enough melanin to protect their skin against harmful rays from the sun develop temporary freckles associated with childhood that usually go away upon puberty, once more melanin is produced. People with the fairest skin often do not produce enough melanin, and so freckles are present after puberty and into adulthood, indicating that individual as a genetic carrier for freckles.

Upon exposure to the sun, freckles will reappear if they have been altered with creams or lasers and not protected from the sun, but do however fade with age in some cases. Freckles are not a skin disorder. People with a predisposition to freckles may be especially susceptible to sunburn and skin cancer, and should therefore take extra care to protect themselves in the sun with a daily sunblock of at least 15 SPF.

Two Types of Freckles
Ephelides is a genetic trait. Its used to describe a freckle that is flat, light brown or red, and fades in the winter. Ephelides are more common in those with light complexions and with the regular use of sunblock, can be suppressed.

Lentigines (also known as sun spots) are freckles that do not fade in the winter. Rather, they form after years of exposure to the sun. Lentigines are more common in older people.

Complexion refers to the natural color, texture, and appearance of the skin, especially that of the face. The word is derived from the Late Latin complexi, which initially referred in general terms to a combination of things, and later in physiological terms, to the balance of humors.

Varying complexionsThe four humours were four fluids that were thought to permeate the body and influence its health. The concept was developed by ancient Greek thinkers around 400 BC. People were thought to be either Choleric, Melancholic, Phlegmatic, or Sanguine.

Complexion was thus thought to be a sign of character. Many surnames arose out of the existence of a complexion whose particularities may have differed from that of the village or townâs population, and thus attracted enough notice to warrant a nickname. The Irish surname Rogan (from Ruadhán) referred to a person with red hair, or a ruddy complexion. The Scottish surname Bain (from bàn) referred to a fair-haired person, while Dunn (from donn) implies brown/dark hair, and Duff (from dubh) implies black hair. The English surname Brown, an extremely common surname in the English-speaking world, was originally applied to anyone with a slightly darker complexion, in the same manner that the surname White was applied to anyone with a particularly light complexion. The surname Gough is derived from the Welsh goch or coch, meaning "red" or "ruddy." King William II of England was called William Rufus ("the Red") because of his ruddy complexion. Ludovico il Moro ("the Moor") was called as such because of his swarthy complexion.




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Title Post: Where/how do gingers get their hideous pigmentation from?
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